Anhedonia and deficits in positive emotional experience in individuals with genetic liability for schizophrenia

Resource Information

The work Anhedonia and deficits in positive emotional experience in individuals with genetic liability for schizophrenia represents a distinct intellectual or artistic creation found in University of Missouri-Kansas City Libraries. This resource is a combination of several types including: Work, Language Material, Books.

Label

Anhedonia and deficits in positive emotional experience in individuals with genetic liability for schizophrenia

Statement of responsibility

By Anna R. Docherty

Creator

• Docherty, Anna R

Contributor

• Kerns, John Gerald, 1971-

Author

• Docherty, Anna R

Thesis advisor

• Kerns, John Gerald, 1971-

Subject

• Dissertations, Academic -- University of Missouri--Columbia -- Psychology
• Electronic dissertations
• Schizophrenia -- Physiological aspects
• Anhedonia.

Genre

• Electronic dissertations

Language

eng

Summary

There is growing evidence that anhedonia--the extent to which an individual reports pleasure or interest in social and physical stimuli--is important to the pathophysiology of schizophrenia. At the same time, some research has suggested that there are different facets of pleasure and positive affect (PA), such as liking vs. wanting (Berridge & Robinson, 1998). Previous research has not directly examined the relationship between anhedonia symptoms and measures of positive affect in relation to genetic liability to schizophrenia. This research examined people with schizophrenia and schizoaffective disorder, their first-degree relatives, and nonpsychiatric controls to assess emotion traits as potential phenotypes for anhedonia in genetic liability for schizophrenia. Multiple methods and measures were used to assess anhedonia and affective traits. There was a general lack of association between interview anhedonia and many facets of PA, coupled with a lack of group differences across PA variables. However, there was general evidence of association of self-reported anhedonia (in both probands and relatives) with many PA variables, suggesting the presence of confounding methodological variance. Significant group differences on a novel behavioral measure of effort for reward were detected. Last, results suggested that ambivalence, long considered relevant to psychosis, is more associated with affect than with liability to schizophrenia

Cataloging source

MUU

Degree

Ph. D.

Dissertation note

Thesis

Dissertation year

2013.

Government publication

government publication of a state province territory dependency etc

Granting institution

University of Missouri--Columbia

Illustrations

illustrations

Index

no index present

Literary form

non fiction

Nature of contents

• dictionaries
• catalogs
• theses