The Resource The developmental liver transcriptome of Rattus norvegicus, by Richard Harrison Chapple

The developmental liver transcriptome of Rattus norvegicus, by Richard Harrison Chapple

Label
The developmental liver transcriptome of Rattus norvegicus
Title
The developmental liver transcriptome of Rattus norvegicus
Statement of responsibility
by Richard Harrison Chapple
Creator
Contributor
Author
Thesis advisor
Subject
Genre
Language
eng
Summary
Our research is involved in the transcriptional dynamics of perinatal liver development. The transcription factors and their downstream effects have been well studied in regards to early liver development, yet perinatal liver development is much less well understood. In an attempt to investigate this area of research, we developed a time course experiment including both pre- and postnatal liver samples whereby RNA sequencing was performed on each of the biological stages. We investigated such areas as gene expression, isoform expression, transcriptional regulation, and post-transcriptional modifications of transcribed molecules. Furthermore, we used a bioinformatics approach to improve upon the reference annotation for known genes. Our research gives insight to the biological phenomenon of late gestational and post parturition liver development. Additionally, we provided annotation for over 1000 regions in the rat reference genome. Further work will include an attempt to investigate novel transcript and gene discovery, as well as an attempt to characterize the extent of RNA editing in perinatal liver development
Cataloging source
MUU
http://library.link/vocab/creatorName
Chapple, Richard Harrison
Degree
M.S.
Dissertation note
Thesis
Dissertation year
2012.
Government publication
government publication of a state province territory dependency etc
Granting institution
University of Missouri--Columbia,
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Taylor, J.
  • Schnabel, Robert D.
http://library.link/vocab/subjectName
  • Liver
  • Perinatology
  • Nucleotide sequence
  • Gene expression
  • Bioinformatics
  • RNA editing
  • Rattus norvegicus
Label
The developmental liver transcriptome of Rattus norvegicus, by Richard Harrison Chapple
Instantiates
Publication
Note
Thesis advisors: Drs. Jeremy F. Taylor and Robert D. Schnabel
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
876615129
Extent
1 online resource (x, 71 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (color)
Specific material designation
remote
System control number
(OCoLC)876615129
Label
The developmental liver transcriptome of Rattus norvegicus, by Richard Harrison Chapple
Publication
Note
Thesis advisors: Drs. Jeremy F. Taylor and Robert D. Schnabel
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
876615129
Extent
1 online resource (x, 71 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (color)
Specific material designation
remote
System control number
(OCoLC)876615129

Library Locations

  • Health Sciences LibraryBorrow it
    2411 Holmes St, Kansas City, Kansas City, MO, 64108, US
    39.083418 -94.575323
  • LaBudde Special CollectionsBorrow it
    800 E 51st St, Kansas City, MO, 64110, US
    39.034642 -94.576835
  • Leon E. Bloch Law LibraryBorrow it
    500 E. 52nd Street, Kansas City, MO, 64110, US
    39.032488 -94.581967
  • Marr Sound ArchivesBorrow it
    800 E 51st St, Kansas City, MO, 64110, US
    39.034642 -94.576835
  • Miller Nichols LibraryBorrow it
    800 E 51st St, Kansas City, MO, 64110, US
    39.035061 -94.576518
  • UMKCBorrow it
    800 E 51st St, Kansas City, MO, 64110, US
    39.035061 -94.576518
  • UMKCBorrow it
    800 E 51st St, Kansas City, MO, 64110, US
Processing Feedback ...