The Resource Part I: Synthesis of functionalized bile acids towards the construction of steroidal macrocycles. Part II: Evaluation and expansion of a modular card game for teaching organic chemistry, Christopher A. Knudtson

Part I: Synthesis of functionalized bile acids towards the construction of steroidal macrocycles. Part II: Evaluation and expansion of a modular card game for teaching organic chemistry, Christopher A. Knudtson

Label
Part I: Synthesis of functionalized bile acids towards the construction of steroidal macrocycles. Part II: Evaluation and expansion of a modular card game for teaching organic chemistry
Title
Part I: Synthesis of functionalized bile acids towards the construction of steroidal macrocycles. Part II: Evaluation and expansion of a modular card game for teaching organic chemistry
Statement of responsibility
Christopher A. Knudtson
Title variation
  • Synthesis of functionalized bile acids towards the construction of steroidal macrocycles
  • Evaluation and expansion of a modular card game for teaching organic chemistry
Creator
Contributor
Author
Degree supervisor
Subject
Genre
Language
eng
Summary
In Part I, the synthesis of chenodeoxychoic acid (CDCA) derivatives towards the construction of unique chemical architectures are reported. Building on previously described methods, CDCA based macrocycles with inner cavities have been synthesized and characterized. Attempts toward oxa-Michael coupling of CDCA monomers to form sulfonate ester linked dimmers is described. CDCA was also functionalized with terminal alkynes (pentynyl, hexynyl, and heptynyl) and aryl iodide and cyclized to from the respective macrocycles. These have been coupled together via oxygen-free Sonogashira reaction conditions to form large barrel-like steroidal architectures. These structures were investigated by 1H NMR, 13C NMR spectroscopy, and HR-MS, and MALDI-TOF spectroscopy. In part II a game to teach organic chemistry, ChemKarta was evaluated as a teaching tool. Analysis of an undergraduate class's impressions of the game showed that Chemkarta was an easy to learn and enjoyable game, but the amount of information in the game could be overwhelming for some students. Furthermore, the modular nature of the game was demonstrated by developing new cards to fit into the examined card set, as well as additional card sets to teach different subjects using the same game rules
Cataloging source
UMK
http://library.link/vocab/creatorDate
1982-
http://library.link/vocab/creatorName
Knudtson, Christopher A.
Degree
Ph.D.
Dissertation note
(Department of Chemistry, School of Pharmacy).
Dissertation year
2019.
Granting institution
University of Missouri-Kansas City,
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
White, Theodore
http://library.link/vocab/subjectName
  • Bile acids
  • Steroids
  • Chemistry, Organic
Label
Part I: Synthesis of functionalized bile acids towards the construction of steroidal macrocycles. Part II: Evaluation and expansion of a modular card game for teaching organic chemistry, Christopher A. Knudtson
Instantiates
Publication
Copyright
Note
  • "A dissertation in Chemistry and Pharmaceutical Sciences."
  • Advisor: Theodore White
  • Vita
Antecedent source
not applicable
Bibliography note
Includes bibliographical references (pages 252-253)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
black and white
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Literature review -- Oxa-Michael strategies toward CDCA dimers -- Synthesis of bile acids derivatives towards macrocycle construction via Sonogashara coupling -- Evaluation and expansion of Chemkarta -- Conclusion -- Appendix A. Functional groups -- Appendix B. Functional Groups Victory and Technique Cards --Appendix C. Structure and bonding -- Appendix D. Name reactions
Control code
1135980750
Dimensions
unknown
Extent
1 online resource (316 pages)
File format
one file format
Form of item
online
Level of compression
mixed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Quality assurance targets
not applicable
Specific material designation
remote
System control number
(OCoLC)1135980750
System details
  • The full text of the dissertation is available as an Adobe Acrobat .pdf file; Adobe Acrobat Reader required to view the file
  • Mode of access: World Wide Web
Label
Part I: Synthesis of functionalized bile acids towards the construction of steroidal macrocycles. Part II: Evaluation and expansion of a modular card game for teaching organic chemistry, Christopher A. Knudtson
Publication
Copyright
Note
  • "A dissertation in Chemistry and Pharmaceutical Sciences."
  • Advisor: Theodore White
  • Vita
Antecedent source
not applicable
Bibliography note
Includes bibliographical references (pages 252-253)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
black and white
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Literature review -- Oxa-Michael strategies toward CDCA dimers -- Synthesis of bile acids derivatives towards macrocycle construction via Sonogashara coupling -- Evaluation and expansion of Chemkarta -- Conclusion -- Appendix A. Functional groups -- Appendix B. Functional Groups Victory and Technique Cards --Appendix C. Structure and bonding -- Appendix D. Name reactions
Control code
1135980750
Dimensions
unknown
Extent
1 online resource (316 pages)
File format
one file format
Form of item
online
Level of compression
mixed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Quality assurance targets
not applicable
Specific material designation
remote
System control number
(OCoLC)1135980750
System details
  • The full text of the dissertation is available as an Adobe Acrobat .pdf file; Adobe Acrobat Reader required to view the file
  • Mode of access: World Wide Web

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