The Resource Implementation of National Pediatric Guidelines to Prevent Chemotherapy Induced Nausea and Vomiting in Children with Cancer, Taryn Sandheinrich

Implementation of National Pediatric Guidelines to Prevent Chemotherapy Induced Nausea and Vomiting in Children with Cancer, Taryn Sandheinrich

Label
Implementation of National Pediatric Guidelines to Prevent Chemotherapy Induced Nausea and Vomiting in Children with Cancer
Title
Implementation of National Pediatric Guidelines to Prevent Chemotherapy Induced Nausea and Vomiting in Children with Cancer
Statement of responsibility
Taryn Sandheinrich
Creator
Subject
Genre
Language
eng
Summary
Purpose: The purpose of this study was to assess the use of supplemental, as needed (prn) pharmacologic interventions for uncontrolled acute chemotherapy induced nausea and vomiting (CINV) in children with cancer after implementation of new pediatric CINV prophylaxis guidelines. Description of Project: A retrospective chart review was completed on forty-three children admitted to the hospital for chemotherapy during a 3 month period in 2017 to document the use of medications given for acute breakthrough CINV. The pre-implementation group received anti-emetics based on the institutional standard of care. A second retrospective chart review was completed on thirty-three children admitted to the hospital for chemotherapy during a 3 month period in 2018 to evaluate use of medications for acute breakthrough CINV. The post-implementation group received anti-emetics based on the new published pediatric guidelines. Patient characteristics, treatment information, and provider compliance with guidelines were collected. Results/Conclusions: Implementation of the guideline by the institution was successful with 91% of patients in the post-intervention group receiving the new anti-emetic regimen to prevent nausea and vomiting. The mean anti-emetic dose in all patients for breakthrough CINV pre-implementation was 4.837±10.4857. Post-implementation, the mean anti-emetic dose for all patients was 3.394±6.432. This was not statistically significant (p =0.462). For patients under 12, the mean anti-emetic dose pre-implementation was 5.8±12.5333 and post-implementation was 3.882±8.1. This was also not statistically significant (p =0.55). Data collected from this project did demonstrate a decrease in the number of breakthrough anti-emetics used in children under 12 years of age likely related to the addition of the drug aprepitant. Although clinical guidelines provide excellence guidance to clinicians, they must always be evaluated for risk versus benefit; adapted to individual patient circumstances as appropriate; and used within the context of expert clinician judgement
Member of
Cataloging source
UMS
http://library.link/vocab/creatorName
Sandheinrich, Taryn
Degree
DNP
Dissertation year
2018
Granting institution
University of Missouri--St. Louis
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/subjectName
  • Cancer in children
  • Chemotherapy
  • Drugs
  • Nausea
  • Vomiting
Label
Implementation of National Pediatric Guidelines to Prevent Chemotherapy Induced Nausea and Vomiting in Children with Cancer, Taryn Sandheinrich
Instantiates
Publication
Note
Title from title page of PDF (University of Missouri--St. Louis, viewed October 23, 2018)
Bibliography note
Includes bibliographical references (pages 17-20)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
1057554721
Extent
1 online resource (23 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)1057554721
Label
Implementation of National Pediatric Guidelines to Prevent Chemotherapy Induced Nausea and Vomiting in Children with Cancer, Taryn Sandheinrich
Publication
Note
Title from title page of PDF (University of Missouri--St. Louis, viewed October 23, 2018)
Bibliography note
Includes bibliographical references (pages 17-20)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
1057554721
Extent
1 online resource (23 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)1057554721

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