Coverart for item
The Resource DDT, lindane, and 2,4-D, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

DDT, lindane, and 2,4-D, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Label
DDT, lindane, and 2,4-D
Title
DDT, lindane, and 2,4-D
Statement of responsibility
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Creator
Contributor
Author
Issuing body
Subject
Language
eng
Summary
The International Agency for Research on Cancer (IARC), the specialized cancer agency of the World Health Organization, has evaluated the carcinogenicity of the insecticides gamma-hexachlorocyclohexane (lindane) and dichlorodiphenyltrichloroethane (DDT) and the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D). After thoroughly reviewing the latest available scientific literature, a Working Group of 26 experts from 13 countries convened by the IARC Monographs Programme classified the insecticide lindane as carcinogenic to humans (Group 1). There was sufficient evidence in humans for the carcinogenicity of lindane for non-Hodgkin lymphoma (NHL).The insecticide DDT was classified as probably carcinogenic to humans (Group 2A), based on sufficient evidence that DDT causes cancer in experimental animals and limited evidence of its carcinogenicity in humans. Epidemiological studies found positive associations between exposure to DDT and NHL, testicular cancer, and liver cancer. There was also strong experimental evidence that DDT can suppress the immune system and disrupt sex hormones. However, overall there was no association between breast cancer and DDT levels measured in samples of blood or fat. The herbicide 2,4-D was classified as possibly carcinogenic to humans (Group 2B), based on inadequate evidence in humans and limited evidence in experimental animals. There is strong evidence that 2,4-D induces oxidative stress, a mechanism that can operate in humans, and moderate evidence that 2,4-D causes immunosuppression, based on in vivo and in vitro studies. However, epidemiological studies did not find strong or consistent increases in risk of NHL or other cancers in relation to 2,4-D exposure
Member of
Cataloging source
MMU
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QV 633.5.H3
NLM item number
IA21I v.113 2017
http://bibfra.me/vocab/lite/organizationName
IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
http://library.link/vocab/relatedWorkOrContributorName
International Agency for Research on Cancer
Series statement
IARC monographs on the evaluation of carcinogenic risks to humans,
Series volume
volume 113
http://library.link/vocab/subjectName
  • DDT
  • Hexachlorocyclohexane
  • 2,4-Dichlorophenoxyacetic Acid
  • Neoplasms
  • Carcinogens
  • Herbicides
  • Insecticides
  • Occupational Exposure
Label
DDT, lindane, and 2,4-D, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Instantiates
Publication
Distribution
Note
"This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 2-9 June 2015."
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
1028240171
Extent
1 online resource (501 pages)
Form of item
online
Isbn
9789283201793
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)1028240171
Label
DDT, lindane, and 2,4-D, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
Publication
Distribution
Note
"This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, which met in Lyon, 2-9 June 2015."
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
1028240171
Extent
1 online resource (501 pages)
Form of item
online
Isbn
9789283201793
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
Specific material designation
remote
System control number
(OCoLC)1028240171

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