Coverart for item
The Resource Biomarker tests for molecularly targeted therapies : key to unlocking precision medicine, Committee on Policy Issues in the Clinical Development and Use of Biomarkers for Molecularly Targeted Therapies ; Laurene A. Graig, Jonathan K. Phillips, and Harold L. Moses, editors ; Board on Health Care Services, Institute of Medicine, the National Academies of Sciences, Engineering, Medicine

Biomarker tests for molecularly targeted therapies : key to unlocking precision medicine, Committee on Policy Issues in the Clinical Development and Use of Biomarkers for Molecularly Targeted Therapies ; Laurene A. Graig, Jonathan K. Phillips, and Harold L. Moses, editors ; Board on Health Care Services, Institute of Medicine, the National Academies of Sciences, Engineering, Medicine

Label
Biomarker tests for molecularly targeted therapies : key to unlocking precision medicine
Title
Biomarker tests for molecularly targeted therapies
Title remainder
key to unlocking precision medicine
Statement of responsibility
Committee on Policy Issues in the Clinical Development and Use of Biomarkers for Molecularly Targeted Therapies ; Laurene A. Graig, Jonathan K. Phillips, and Harold L. Moses, editors ; Board on Health Care Services, Institute of Medicine, the National Academies of Sciences, Engineering, Medicine
Creator
Contributor
Editor
Issuing body
Subject
Language
eng
Summary
"Every patient is unique, and the evolving field of precision medicine aims to ensure the delivery of the right treatment to the right patient at the right time. In an era of rapid advances in biomedicine and enhanced understanding of the genetic basis of disease, health care providers increasingly have access to advanced technologies that may identify molecular variations specific to an individual patient, which subsequently can be targeted for treatment. Known as biomarker tests for molecularly targeted therapies, these complex tests have the potential to enable the selection of the most beneficial treatment (and also to identify treatments that may be harmful or ineffective) for the molecular underpinnings of an individual patient's disease. Such tests are key to unlocking the promise of precision medicine. Biomarker tests for molecularly targeted therapies represent a crucial area of focus for developing methods that could later be applicable to other areas of precision medicine. The appropriate regulatory oversight of these tests is required to ensure that they are accurate, reliable, properly validated, and appropriately implemented in clinical practice. Moreover, common evidentiary standards for assessing the beneficial impact of biomarker-guided therapy selection on patient outcomes, as well as the effective collection and sharing of information related to those outcomes, are urgently needed to better inform clinical decision making. Biomarker Tests of Molecularly Targeted Therapies examines opportunities for and challenges to the use of biomarker tests to select optimal therapy and offers recommendations to accelerate progress in this field. This report explores regulatory issues, reimbursement issues, and clinical practice issues related to the clinical development and use of biomarker tests for targeting therapies to patients. Properly validated, appropriately implemented biomarker tests hold the potential to enhance patient care and improve outcomes, and therefore addressing the challenges facing such tests is critical"--Publisher's description
Cataloging source
CUS
Dewey number
610.28
Illustrations
illustrations
Index
no index present
LC call number
R853.B54
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QW 541
http://bibfra.me/vocab/lite/organizationName
National Academies of Sciences, Engineering, and Medicine (U.S.)
http://library.link/vocab/relatedWorkOrContributorName
  • Graig, Laurene A.
  • Phillips, Jonathan
  • Moses, Harold L.
http://library.link/vocab/subjectName
  • Biochemical markers
  • Gene therapy
  • Biomarkers
  • HEALTH & FITNESS
  • HEALTH & FITNESS
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Biochemical markers
  • Gene therapy
Label
Biomarker tests for molecularly targeted therapies : key to unlocking precision medicine, Committee on Policy Issues in the Clinical Development and Use of Biomarkers for Molecularly Targeted Therapies ; Laurene A. Graig, Jonathan K. Phillips, and Harold L. Moses, editors ; Board on Health Care Services, Institute of Medicine, the National Academies of Sciences, Engineering, Medicine
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Contents
Front matter -- Summary -- Introduction -- Envisioning a rapid learning system for biomarker tests for molecularly targeted therapies -- Supportive policy environment for biomarker tests for molecularly targeted therapies -- Supporting data infrastructure for biomarker tests for molecularly targeted therapies -- Processes to improve patient care -- Appendix A: Committee member and staff biographies -- Appendix B: Coding: payment infrastructure for biomarker tests for molecularly targeted therapies -- Appendix C: Information-gathering sessions and speakers -- Glossary
Control code
952644751
Extent
1 online resource (xxiv, 268 pages)
Form of item
online
Isbn
9780309381352
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
color illustrations
Specific material designation
remote
System control number
(OCoLC)952644751
Label
Biomarker tests for molecularly targeted therapies : key to unlocking precision medicine, Committee on Policy Issues in the Clinical Development and Use of Biomarkers for Molecularly Targeted Therapies ; Laurene A. Graig, Jonathan K. Phillips, and Harold L. Moses, editors ; Board on Health Care Services, Institute of Medicine, the National Academies of Sciences, Engineering, Medicine
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Contents
Front matter -- Summary -- Introduction -- Envisioning a rapid learning system for biomarker tests for molecularly targeted therapies -- Supportive policy environment for biomarker tests for molecularly targeted therapies -- Supporting data infrastructure for biomarker tests for molecularly targeted therapies -- Processes to improve patient care -- Appendix A: Committee member and staff biographies -- Appendix B: Coding: payment infrastructure for biomarker tests for molecularly targeted therapies -- Appendix C: Information-gathering sessions and speakers -- Glossary
Control code
952644751
Extent
1 online resource (xxiv, 268 pages)
Form of item
online
Isbn
9780309381352
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
color illustrations
Specific material designation
remote
System control number
(OCoLC)952644751

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