The Resource A novel framework for protein structure prediction, by Rajkumar Bondugula, (electronic resource)

A novel framework for protein structure prediction, by Rajkumar Bondugula, (electronic resource)

Label
A novel framework for protein structure prediction
Title
A novel framework for protein structure prediction
Statement of responsibility
by Rajkumar Bondugula
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
Proteins are one of the most important molecules in the life processes. The structure of a protein is essential in understanding the function of a protein at the molecular level. Due to rapid progress in sequencing technologies, the gap between the proteins whose structure is known and the proteins whose structure needs to be characterized is rapidly increasing. To address this problem, we are developing a novel framework to computationally predict many aspects of proteins like secondary structure, solvent accessibility, contact map and finally, the tertiary structure itself. We have applied various computational techniques including the fuzzy k-nearest neighbor algorithm, the multi-dimensional scaling method, and the least-squares minimization, in the structure predictions. Our framework uses the evolutionary information more effectively than traditional template based methods, while it has a better potential to utilize the information in PDB than the other evolutionary information based methods. Our methods show better performance in prediction accuracy and computational time than many other tools
Cataloging source
MUU
http://library.link/vocab/creatorDate
1980-
http://library.link/vocab/creatorName
Bondugula, Rajkumar
Degree
Ph.D.
Dissertation year
2007.
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorDate
1965-
http://library.link/vocab/relatedWorkOrContributorName
Xu, Dong
http://library.link/vocab/subjectName
  • Proteins
  • Fuzzy algorithms
  • Evolutionary computation
Target audience
specialized
Label
A novel framework for protein structure prediction, by Rajkumar Bondugula, (electronic resource)
Instantiates
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on March 23, 2009)
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
316802454
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)316802454
System details
Mode of access: World Wide Web
Label
A novel framework for protein structure prediction, by Rajkumar Bondugula, (electronic resource)
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Title from title screen of research.pdf file (viewed on March 23, 2009)
  • Vita
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
mixed
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
316802454
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)316802454
System details
Mode of access: World Wide Web

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